Buy Generic Nuvigil (Armodafinil) | Information Page

US Brand Name: Nuvigilwaklert 150

Active substance: Armodafinil

Indian Brand: Waklert

Manufacturer: Sun Pharma

Dosage: 50mg / 150mg

Type of packaging:  10 tabs in pack

Delivery time: 7 – 14 days.

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What is Armodafinil?

Armodafinil is currently FDA-approved to treat excessive daytime sleepiness associated with obstructive sleep apnea, narcolepsy, and shift work disorder. It is commonly used off-label to treat attention deficit hyperactivity disorder, chronic fatigue syndrome, and major depressive disorder. It has been shown to improve vigilance in air traffic controllers.

Armodafinil is approved by the U.S. FDA for the treatment of narcolepsy and shift work sleep disorder, and as an adjuvant therapy for obstructive sleep apnea. For narcolepsy and obstructive sleep apnea, armodafinil is taken as a once daily 150 mg or 250 mg dose in the morning. For shift work sleep disorder, 150 mg of armodafinil are taken one hour prior to starting work. Slow dose titration is needed to mitigate some side effects.

Mechanism of Action

For people who have stopped drinking, Naltrexone reduces the craving for alcohol which many alcohol dependent people experience when they quit drinking. It is not fully understood how Naltrexone works to reduce the craving for alcohol, but some scientists believe it works by affecting the neural pathways in the brain where the neurotransmitter dopamine is found.

Nuvigil (armodafinil) is a single-isomer of modafini. The exact mechanism of action is unknown. Armodafinil belongs to a class of drugs known as eugeroics, which are stimulants that provide long-lasting mental arousal. Pharmacologically, armodafinil does not bind to or inhibit several receptors and enzymes potentially relevant for sleep/wake regulation. Armodafinil is not a direct- or indirect-acting dopamine receptor agonist. However, in vitro, both armodafinil and modafinil bind to the dopamine transporter and inhibit dopamine reuptake.

 Adverse effects

In placebo-controlled studies, the most commonly observed side effects were headache, nausea, dizziness, and insomnia.

Generic NUVIGIL (armodafinil) is a wakefulness-promoting agent for oral administration. Armodafinil is the R-enantiomer of modafinil which is a 1:1 mixture of the Rand S-enantiomers. The chemical name for armodafinil is 2-[(R)-(diphenylmethyl)sulfinyl]acetamide. The molecular formula is C15H15NO2S and the molecular weight is 273.35.

The chemical structure is:


EXNUVIGIL® (armodafinil) Structural Formula Illustration